Independent 

2025

81. Alexander J. Hughes Julie A. Talbert, and Steven D. Townsend*. Discovery of Iboga-Derived Ligands for the s2 Receptor. 2025. In Revisions.
80. Harpreet Kaur, Julie A. Talbert, Syed Azmal Ali, M. Kay Washington, Daniel P Barry, Keith T Wilson, Richard M. Peek Jr, Sari A. Acra, Steven D. Townsend, Fang Yan*. EGF receptor transactivation in intestinal epithelial cells by a human milk oligosaccharide mediates prevention of colitis in adulthood. 2025​. Under Review.
79. C. Elizabeth Adams and Steven D. Townsend.* Studies Toward the Synthesis of Yaretol: An Unexpected Rearrangement en route to the Tricyclic Core. 2025. Tetrahedron. 10.1016/j.tet.2025.134619.
78. Julie A. Talbert and Steven D. Townsend*. Human Milk as a Complex Natural Product. 2025. ​Nat. Prod. Rep.10.1039/D4NP00058G.

2024

​77. Julie A. Talbert and Steven D. Townsend*.Evaluation of Kochetkov Aminal Hydrolysis under Acidic, Alkaline, and Neutral Conditions. 2024. ​DOI: 10.1016/j.carres.2024.109253.
76. C. Elizabeth Adams, Sabrina K. Spicer, Jennifer A. Gaddy, and Steven D. Townsend*. Synthesis of Phosphoethanolamine Cellulose Mimetics: Characterization of their Adherence-Modulating Properties in Escherichia coli. 2024. ACS Infect. Dis. 10.1021/acsinfecdis.4c00267.
​75. Alexander J. Hughes, Charles R. Hamelink, and Steven D. Townsend*. Disrupting Substance Use Disorder: The Chemistry of Iboga Alkaloids. ​2024. Eur. J. Org. Chem. DOI: 10.1002/ejoc.202400432
​74. Alexander J. Hughes and Steven D. Townsend*. Total Synthesis of Tabernanthine and Ibogaline: Rapid Access to Nosyl Tryptamines. 2024. Eur. J. Org. Chem. DOI: 10.1002/ejoc.202400442
73. Kasey M. Schalich , Matthew A. Buendia , Harpreet Kaur , Yash A Choksi , M. Kay Washington , Gabriela S. Codreanu , Stacy D. Sherrod , John A. McLean, Richard M Peek , Sari Acra , Steven D. Townsend, Fang Yan*. A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism. 2024. mBio. DOI: 10.1128/mbio.00298-24
72. Alexander J. Hughes and Steven D. Townsend*. Oxidative Construction of Unusual Indole-Derived Intermediates en Route to Conodusine A. 2024. Tetrahedron Lett. DOI: 10.1016/j.tetlet.2024/154931.
71. Alexander J. Hughes and Steven D. Townsend*. Total Synthesis of Ervaoffine J & K. 2024. Chem. Eur. J. DOI: 10.1002/chem.202303985. 

2023

70. Victoria R Stephens, Rebecca E Moore, Sabrina K Spicer, Julie A Talbert, Jacky Lu, Riya Chinni, Schuyler A Chambers, Steven D Townsend, Shannon D Manning, Lisa M Rogers, David M Aronoff, Zer Vue, Kit Neikirk, Antentor O Hinton Jr, Steven M Damo, Kristen N Noble, Alison J Eastman, Monique M McCallister, Kevin G Osteen, Jennifer A Gaddy*. Environmental Toxicant Exposure Paralyzes Human Placental Macrophage Responses to Microbial Threat. 2023. ACS Infect. Dis. DOI: acsinfecdis.3c00490.
69. ​Rebecca E. Moore, Sabrina K. Spicer, Jacky Lu, Schuyler A. Chambers, Kristen N. Noble, Jonathan Lochner, Shannon D. Manning, Steven D. Townsend*, Jennifer A. Gaddy*. The utility of human milk oligosaccharides against Group B Streptococcus infections of reproductive tissues and cognate adverse pregnancy outcomes. 2023. ACS Cent. Sci. DOI: 10.1021/acscentsci.3c00101
68. Xavier S. Streety, Jennifer C. Obike, and Steven D. Townsend*. A Hitchhiker’s Guide to Problem Selection in Carbohydrate Synthesis. ​2023. ACS Cent. Sci. DOI: 10.1021/acscentsci.3c00507.
67. Alfred Mays, Angela Byars-Winston, Antentor Hinton, Andrea G Marshall, Annet Kirabo, Avery August, Bianca J Marlin, Blake Riggs, Blanton Tolbert, Celestine Wanjalla, Chad Womack, Chantell S Evans, Christopher Barnes, Chrystal Starbird, Clintoria Williams, Corey Reynolds, Cornelius Taabazuing, Craig E Cameron, Debra D Murray, Derek Applewhite, Derrick J Morton, Dexter Lee, Dionna W Williams, Donald Lynch, Donita Brady, Erin Lynch, Florentine UN Rutaganira, Gustavo M Silva, Haysetta Shuler, Ishmail Abdus Saboor, Jamaine Davis, Kafui Dzirasa, Latanya Hammonds-Odie, Loretta Reyes, Mariya T Sweetwyne, Melanie R McReynolds, Michael DL Johnson, Nathan A Smith, Nikea Pittman, Olujimi A Ajijola, Quinton Smith, Renã AS Robinson, Samantha C Lewis, Sandra A Murray, Sherilynn Black, Sonya E Neal, Stanley Andrisse, Steven Townsend, Steven M Damo, Theanne N Griffith, W Marcus Lambert, William M Clemons. Juneteenth in STEMM and the barriers to equitable science. Cell. 2023. DOI.10.1016/j.cell.2023.05.016.
​66. Alexander J. Hughes and Steven D. Townsend*. Gram-Scale Total Synthesis of +/- Ibogamine. 2023. Org. Lett. DOI: 10.1021/acs.orglett.3c01595.
​65. Rebecca E. Moore, Sabrina K. Spicer, Jacky Lu, Schuyler A. Chambers, Kristen N. Noble, Jonathan Lochner, Karla Vasco, Shannon D. Manning, Steven D. Townsend* and Jennifer A. Gaddy*. Anti-Biofilm Activity of Human Milk Oligosaccharides in Clinical Strains of Streptococcus agalactiae with Diverse Capsular and Sequence Types. ​2023. chembiochem. DOI: https://doi.org/10.1002/cbic.202200643.
2022
64. Jacky Lu, Rebecca E. Moore, Sabrina K. Spicer, Ryan S. Doster, Miriam A. Guevara, Jamisha D. Francis, Kristen N. Noble, Lisa M. Rogers, Julie Talbert, David M. Aronoff, Shannon D. Manning, Steven D. Townsend, and Jennifer A. Gaddy*. Streptococcus agalactiae npx is required for survival in placental macrophages and full virulence in a model of ascending vaginal infection during pregnancy. 2022. mBio. DOI: 10.1128/mbio.02870-22.
63. Julie A. Talbert, Jacky Lu, Sabrina K. Spicer, Rebecca E. Moore, Steven D. Townsend*, Jennifer A. Gaddy.* Ameliorating Adverse Perinatal Outcomes with Lactoferrin: An Intriguing Chemotherapeutic Intervention. 2022. Bioorg. Med. Chem. DOI: 10.1016/j.bmc.2022.117037.
  • Yimon Aye Young Investigator Special Issue.
62. Michelle Korir, Ryan Doster, Jacky Lu, Miriam Guevara, Sabrina Spicer, Rebecca Moore, Jamisha Francis, Lisa Rogers, Kathryn Haley, Amondrea Blackman, Kristen Noble, Alison Eastman, Janice Williams, Steven Damo, Kelli Boyd, Steven Townsend, C. Henrique Serezani, David Aronoff, Shannon Manning, and Jennifer Gaddy. Streptococcus agalactiae cadD promotes intracellular survival in macrophages and ascending infection during pregnancy. 2022. Nat. Commun. DOI:10.1038/s41467-022-32916-7.
61. Sabrina K. Spicer, Jennifer A. Gaddy, and Steven D. Townsend*. Recent Advances on Human Milk Oligosaccharide Antimicrobial Activity. 2022. Curr. Opin. Chem. Biol. DOI: 10.1016/j.cbpa.2022.102202.
60. ​Johny M. Nguyễn, Cleo S. Evans, Nicole M. Wright, and Steven D. Townsend.* Synthesis of the Aeromonas veronii strain Bs8 OPS disaccharide repeating unit. 2022. Carb. Res. DOI: 10.1016/j.carres.2022.108530
2021
59. Rebecca E. Moore, Harrison C. Thomas, Jennifer A. Gaddy*, and Steven D. Townsend.* GalactoOligosaccharide Supplementation Modulates Bacterial Competition in a Group B Streptococcus - Streptococcus salivarius Two Species Microbiome. 2021. Chembiochem. DOI: 10.1002/cbic.202100559.
58.  Sabrina K. Spicer, Rebecca E. Moore, Jacky Lu, Miriam A. Guevara, Dana R. Marshall, Shannon D. Manning, Steven M. Damo, Steven D. Townsend*, and Jennifer A. Gaddy.* Anti-biofilm activity of human milk oligosaccharides against multi-drug resistant and susceptible isolates of Acinetobacter baumannii. 2021. ACS Infect. Dis. DOI: 10.1021/acsinfecdis.1c00420.
57.  Steven D. Townsend*.  Glycoscience in Infectious Diseases. ACS Infect. Dis. 2021. DOI: 10.1021/acsinfecdis.1c00524
56. Rebecca E. Moore, Steven D. Townsend,* and Jennifer A. Gaddy.* The Diverse Antimicrobial Activities of Human Milk Oligosaccharides Against Group B Streptococcus. Chembiochem. 2021. DOI: 10.1002/cbic.202100423.
55. Gang Zhao, Jessica Williams, M. Kay Washington, Steven D. Townsend, Fang Yan.* 2’-fucosyllactose Ameliorates Chemotherapy-Induced Intestinal Mucositis by Protecting Intestinal Epithelial Cells Against Apoptosis. 2021. Cell. Mol. Gastroenterol. Hepatol. DOI: 10.1016/j.jcmgh.2021.09.015.
54. Jacky Lu, Miriam A. Guevara, Jamisha D. Francis, Sabrina K. Spicer, Rebecca E. Moore, Schuyler A. Chambers, Kelly M. Craft, Shannon D. Manning, Steven D. Townsend*, Jennifer A. Gaddy* Analysis of susceptibility to the antimicrobial and anti-biofilm activity of human milk lactoferrin in clinical strains of Streptococcus agalactiae with diverse capsular and sequence types. 2021. ​Front. Cell. Infect. Microbiol. DOI:10.3389/fcimb.2021.740872.
53. Johny M. Nguyen and Steven D. Townsend.* Total Synthesis of the Photorhabdus temperata ssp. Cinereal 3240 Zwitterionic Trisaccharide Repeating Unit. 2021. ​​Org. Lett. DOI: 10.1021/acs.orglett.1c02023.
52. Lianyan Xu and Steven D. Townsend.* Synthesis as an Expanding Resource in Human Milk Science. 2021. J. Am. Chem. Soc. DOI: 10.1021/jacs.1c05599.
51.  Jacky Lu, Kathryn P. Haley, Jamisha D. Francis, Miriam A. Guevara, Ryan S. Doster, Kelly M. Craft, Rebecca E. Moore, Schuyler A. Chambers, Alberto G. Delgado, Maria Blanca Piazuelo, Steven M. Damo, Steven D. Townsend*, Jennifer A. Gaddy*. The innate immune glycoprotein lactoferrin represses the Helicobacter pylori cag type IV secretion system. 2021. Chembiochem. DOI: 10.1002/cbic.202100249.
50. Eric D. Huseman, Jo Ann Byl, Scott M. Chapp, Nathan D. Schley, Neil Osheroff, and Steven D. Townsend*. Synthesis and Cytotoxicity Evaluation of Arimetamycin A and its Daunorubicin and Doxorubicin Hybrids. ​2021. ACS Cent. Sci. DOI: 10.1021/acscentsci.1c00040
49. Tyra Avery, RaNashia L. Boone, Jacky Lu, Sabrina Spicer, Miriam A. Guevara, Rebecca E. Moore, Schuyler A. Chambers, Shannon D. Manning, Leon Dent, Dana Marshall, Steven M. Damo, Steven D. Townsend*, Jennifer A. Gaddy*. Analysis of the antimicrobial and anti-biofilm activity of human milk lactoferrin compared to bovine lactoferrin against multi-drug resistant and susceptible Acinetobacter baumannii clinical isolates. 2021. ACS Infect. Dis. DOI: /10.1021/acsinfecdis.1c00087
48. Kristen Noble, Jacky Lu, Miriam Guevara, Ryan Doster, Schuyler Chambers, Lisa Rogers, Rebecca Moore, Sabrina Spicer, Alison Eastman, Jamisha Francis, Shannon Manning, Lakshmi Rajagopal, David Aronoff, Steven Townsend, and Jennifer Gaddy*. Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during Pregnancy. 2021. ACS Infect. Dis. DOI 10.1021/acsinfecdis.1c00182
47. C. Elizabeth Adams‡, Alexander J. Hughes‡, and Steven D. Townsend*. Harnessing Anomeric Anions to Synthesize α- and β-Deoxyaminoglycosides. ​2021. Trends in Chemistry. DOI: 10.1016/j.trechm.2021.04.008
  • Invited Spotlight
46. Johny M. Nguyen‡, Rebecca E. Moore‡, Sabrina K. Spicer, Jennifer A. Gaddy*, and Steven D. Townsend.* Synthetic Phosphoethanolamine Cellobiose Promotes Escherichia coli Biofilm Formation and Congo Red Binding. ​2021. Chembiochem. DOI: 10.1002/cbic.202000869
45. Eric D. Huseman and Steven D. Townsend. Synthesis of a Lemonose Thioglycoside Donor from D-Threonine. 2021.​ Tet. Lett. DOI: 10.1016/j.tetlet.2021.153097
  • Invited Submission on the occasion of Prof. Boger's Tetrahedron Prize.
44. Jacky Lu, Jamisha Francis, Miriam Guevara, Rebecca Moore, Schuyler Chambers, Ryan Doster, Alison Eastman, Lisa Rogers, Kristen Noble, Shannon Manning, Steven Damo, David M. Aronoff, Steven Townsend*, and Jennifer Gaddy*. Antibacterial and anti-biofilm activity of the human breast milk glycoprotein lactoferrin against Group B Streptococcus. ​2021. Chembiochem. DOI: 10.1002/cbic.202100016
  • Very Important Paper
  • Chemical Translational Biology Special Issue
43. Alison Eastman, Rebecca E. Moore, Steven D. Townsend, Jennifer A. Gaddy, and David M. Aronoff. The influence of obesity and associated fatty acids on placental inflammation. Clin. Ther. 2021. DOI: 10.1016/j.clinthera.2020.12.018
42. Rebecca E. Moore, Lianyan L. Xu, and Steven D. Townsend*. Prospecting Human Milk Oligosaccharides as a Defense Against Viral Infections. ACS Infect. Dis. 2021. DOI. 10.1021/acsinfecdis.0c00807
41. Ranashia L. Boone; Briana Whitehead; Tyra M. Avery; Jacky Lu; Jamisha D. Francis; Miriam Guevara; Rebecca E. Moore; Schuyler Chambers; Ryan Doster; Shannon D. Manning; Steven D. Townsend; Leon Dent; Dana Marshall; Jennifer Gaddy; Steven M. Damo. Analysis of virulence phenotypes and antibiotic resistance in clinical strains of Acinetobacter baumannii isolated in Nashville, Tennessee. BMC Microbiology. 2021. DOI: 10.1186/s12866-020-02082-1
2020
40. Miriam A. Guevara, Jacky Lu, Rebecca E. Moore, Schuyler A. Chambers, Alison J. Eastman, Jamisha D. Francis, Kristen N. Noble, Ryan S. Doster, Kevin G. Osteen, Steven M. Damo, Shannon D. Manning, David M. Aronoff, Natasha B. Halasa, Steven D. Townsend*, and Jennifer A. Gaddy*. Vitamin D and Streptococci: The Interface of Nutrition, Host Immune Response, and Antimicrobial Activity in Response to Infection. ACS Infect. Dis. 2020. DOI: 10.1021/acsinfecdis.0c00666.
39. Jacky Lu, Jamisha Francis, Kathryn P. Haley, Kelly M. Craft, Rebecca E. Moore, Schuyler A. Chambers, David M. Aronoff, Kevin Osteen, Steven M. Damo, Shannon Manning, Steven D. Townsend*, and Jennifer A. Gaddy*. Lactoferrin: a critical mediator of both host immune response and antimicrobial activity in response to streptococcal infections. ​ACS Infect. Dis. 2020. DOI: 10.1021/acsinfecdis.0c00050.
38. Rebecca E. Moore†, Kelly M. Craft†, Lianyan L. Xu†, Schuyler A. Chambers, Johny M. Nguyen, Keevan C. Marion, Jennifer A. Gaddy*, and Steven D. Townsend*. Leveraging Stereoelectronic Effects in Biofilm Eradication: Synthetic b-Amino Human Milk Oligosaccharides Impede Microbial Adhesion as Observed by Scanning Electron Microscopy. 2020. J. Org. Chem. ​ASAP. DOI: 10.1021/acs.joc.0c01958
37.  ​Schuyler A. Chambers and Steven D. Townsend*. Two-step conversion of unprotected oligosaccharides to generate bioorthogonal oligosaccharide tool compounds. ​MethodsX. 2020, 100996. DOI: 10.1016/j.mex.2020.100996
36. Olugbeminiyi O. Fadeyi*, Marie C. Hefern*, Shanina Sanders Johnson*, and Steven D. Townsend*. What Comes Next? Simple Practices to Improve Diversity in Science. ACS Cent. Sci. 2020. DOI: 10.2021/acscentsci.0c00905 
35. ​Schuyler A. Chambers and Steven D. Townsend*.  Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis. Biochem. Soc. Transac. 2020. DOI: 10.1042/BST20191144.
  • # invited submission to Biochemical Society Transactions. 
34. ​ Steven D. Townsend*. Strategies and Tactics for Achieving Work-Life Integration as a Junior Faculty Member. Chem. Eur. J. 2020. ASAP. DOI: 10.1002/chem.202000967
  • invited "Scientific Voice" communication for the 25th anniversary of Chemistry a European Journal
33. ​Schuyler A. Chambers, Jennifer A. Gaddy*, and Steven D. Townsend*. Synthetic Ellagic Acid Glycosides Inhibit Early-Stage Adhesion of Streptococcus agalactiae Biofilms as Observed by Scanning Electron Microscopy. Chem. Eur. J. 2020. ​DOI: 10.1002/chem.202000354
32. Alexandre Carvalho, Jacky Lu, Jamisha D. Francis, Rebecca E. Moore, Kathryn P. Haley, Ryan S. Doster, Steven D. Townsend, Jeremiah G. Johnson, Steven M. Damo, and Jennifer A. Gaddy*. S100A12 in Digestive Diseases and Health: A Scoping Review. Gastroent. Res. Pract. 2020, 2868373. DOI: 10.1155/2020/2868373
31. Schuyler A. Chambers,@ Rebecca E. Moore,@ Kelly M. Craft, Harrison C. Thomas#, Rishub Das#, Simona G. Codreanu, Stacy D. Sherrod, David M. Aronoff, John A. McLean, Jennifer A. Gaddy*, and Steven D. Townsend*. A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations that Result in Potentiation of Trimethoprim. mBIO. ​2020. 11, 2, e00076-20. ​DOI:10.1128/mBio.00076-20.
  • @ equal contribution
  • # undergraduate co-author
30. Lianyan L. Xu,@ Lawrence J. Berg,@# D. Jamin Keith, and Steven D. Townsend*. An Effective Method to Functionalize Alcohols with Phosphocholine. Org. Biomol. Chem. 2020, 18, 767-770. DOI: 10.1039/C9OB02582K
  • @ equal contribution
  • # undergraduate co-author
29. ​Schuyler A. Chambers and Steven D. Townsend*. Bioorthogonal Human Milk Oligosaccharide Probes for Antimicrobial Target Identification within Streptococcus agalactiae. Carbohydr. Res. 2020, 488, 107895. ​DOI: 10.1016/j.carres.2019.107895
2019
28. ​Rebecca E. Moore and Steven D. Townsend*. Building the Microbiome: Temporal Development of the Gut Flora. 2019. Open Biology. 9:190128. DOI: 10.1098/rsob.190128.
  • Invited review article​​
27.  ​D. Jamin Keith and Steven D. Townsend*. Total Synthesis of the Congested, Bisphosphorylated Morganella morganii Zwitterionic O-Chain Trisaccharide Repeating Unit. J. Am. Chem. Soc. 2019​. 141, 32, 12939-12945.  DOI: 10.1021/jacs.9b06830
​26. Kelly M. Craft and Steven D. Townsend*. Mother Knows Best: Deciphering the Antibacterial Properties of Human Milk Oligosaccharides. Acc. Chem. Res. 2019. 52, 3, 760-768. DOI: 10.1021/acs.accounts.8b00630
  • Editors Choice Article. Open access!​
  • Most Downloaded, February 2019!
25. Steven D. Townsend*. Human Milk Oligosaccharides: Defense Against Pathogens. Breastfeed. Med. 2019, 14, S1, S5-S6. DOI:10.1089/bfm.2019.0039
24.  ​Kelly M. Craft, Johny M. Nguyen, Lawrence J. Berg#, and Steven D. Townsend*.Methicillin-Resistant Staphylococcus aureus (MRSA): Antibiotic-Resistance and the Biofilm Phenotype. Med. Chem. Comm. 2019. 10, 1231-1241. DOI:10.1039/C9MD00044E. DOI: 10.1039/C9MD00044E
  • Invited review article to the Antibiotic Resistance issue of MedChemComm
  • # undergraduate co-author
​23. Kelly M. Craft, Harrison C. Thomas,# and Steven D. Townsend*. Interrogation of Human Milk Oligosaccharide Fucosylation Patterns for Structural Antimicrobial and Antibiofilm Trends in Group B Streptococcus. ACS Infect. Dis. 2019, 4, 1755-1765. DOI:10.1021/acsinfecdis.8b00234
  • # undergraduate co-author
​22. Kelly M. Craft and Steven D. Townsend*. 1-Amino-2′-fucosyllactose inhibits biofilm formation by Streptococcus agalactiae. J. Antibiot. 2019, 72, 507-512. DOI:10.1038/s41429-019-0151-6.
  • Invited research paper for the special issue dedicated to Prof. Sam Danishefsky​​
21. Kelly M. Craft, Harrison C. Thomas,# and Steven D. Townsend*. Sialylated Variants of Lacto-N-Tetraose Exhibit Antimicrobial Activity Against Group B Streptococcus. Org. Biomol. Chem. 2019.1893-1900, DOI: 10.1039/C8OB02080A
  • HOT articles collection
  • Invited research paper for the New Talent Issue
  • # undergraduate co-author
2018
20. Eleni Beli, Yuanqing Yan, Leni Moldovan, Cristiano P. Vieira, Ruli Gao, Yaqian Duan, Ram Prasad, Ashay Bhatwadekar,Fletcher A. White, Steven D. Townsend, Luisa Chan, Caitlin N. Ryan, Daniel Morton, Emil G. Moldovan, Fang-I Chu,Gavin Y. Oudit, Hartmut Derendorf, Luciano Adorini, Xiaoxin X. Wang, Carmella Evans-Molina, Raghavendra G. Mirmira, Michael E. Boulton, Mervin C. Yoder, Qiuhong Li, Moshe Levi, Julia V. Busik, and Maria B. Grant. Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes. 2018, 67, 1867-1879. DOI: 10.2337/db18-0158. 
​19. Kelly M. Craft, Jennifer A. Gaddy, and Steven D. Townsend*. Human Milk Oligosaccharides Sensitize Group B Streptococcus to Clindamycin, Erythromycin, Gentamycin, and Minocycline on a Strain Specific Basis. ACS Chem. Bio. 2018, 13, 2020-2026.  ​DOI: 10.1021/acschembio.8b00661
18. Schuyler A. Chambers, Jenna M. DeSousa, Eric D. Huseman, and Steven D. Townsend*. The DARK Side of Total Synthesis: Strategies and Tactics in Psychoactive Drug Production. ACS Chem. Neurosci. 2018, 9, 2307-2330. DOI: 10.1021/acschemneuro.7b00528
  • Invited review article
17. D. Jamin Keith, Stefan A. Maraslinger, Alexander W. Sasse, and Steven D. Townsend*. One-pot Microwave-assisted Conversion of Anomeric Nitrate-esters to Trichloroacetimidates. J. Vis. Exp. 2018, 131, e56610, 1-7. DOI: 10.3791/5661
​16. Dorothy L. Ackerman,# Kelly M. Craft,# Ryan S. Doster, Jörn-Hendrik Weitkamp, David M. Aronoff, Jennifer A. Gaddy, and Steven D. Townsend*. Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides Against Streptococcus agalactiae, Staphylococcus aureus,and Acinetobacter baumannii. ACS Infect. Dis. 2018. 4, 315-324. DOI: 10.1021/acsinfecdis.7b00183
  • # equal contribution
  • Most read article for December 2017!
15. Kelly M. Craft and Steven D. Townsend*.  The Human Milk Glycome as a Defense Against Infectious Diseases.  ACS Infect. Dis. 2018. 4, 77-83. DOI: 10.1021/acsinfecdis.7b00209
  • ​Invited perspective
2017
14. Yong Guan and Steven D. Townsend*.  Metal-Free Synthesis of Unsymmetrical Organoselenides and Selenoglycosides.  Org. Lett. 2017, 19, 5252-5255. DOI:10.1021/acs.orglett.7b02526
13. Dorothy L. Ackerman, Ryan S. Doster, Jörn-Hendrik Weitkamp, David M. Aronoff, Jennifer A. Gaddy, and Steven D. Townsend*.  Human Milk Oligosaccharides Exhibit Antimicrobial and Anti-Biofilm Properties Against Group B Streptococcus.  ACS Infect. Dis. 2017, 3, 595-605. DOI: 10.1021/acsinfecdis.7b00064
12.  D. Jamin Keith and Steven D. Townsend*.  Direct, Microwave-Assisted Substitution of Anomeric Nitrate-Esters. Carbohydr. Res. 2017, 442, 20-24.
​​11.  Kelly M. Craft and Steven D. Townsend*. Synthesis of Lacto-N-Tetraose. Carbohydr. Res. 2017, 440-441, 43-50.
10.  Dorothy L. Ackerman, Kelly M. Craft, and Steven D. Townsend*.  Infant Food Applications of Complex Carbohydrates:  Structure, Synthesis, and Function.  Carbohydr. Res. 2017, 437, 16-27.
Graduate and Postdoctoral Work
9.  Steven D. Townsend, Audrey G. Ross, Kai Liu, and Samuel J. Danishefsky*.  Stereospecific Cis and Trans Ring Fusions Arising From Common Intermediates.  Proc. Natl. Acad. Sci. U.S.A. 2014, 111(22), 7931-7935.
8.  Steven D. Townsend and Gary A. Sulikowski*.  Progress toward the Total Synthesis of Bielschowskysin.  Org. Lett. 2013, 15(19), 5096-5098.  
7.  Audrey G. Ross, Steven D. Townsend, and Samuel J. Danishefsky*.  Halocycloalkenones as Diels-Alder Dienophiles.  Applications to Generating Useful Structural Patterns.  J. Org. Chem. 2013, 78(1), 204-210. Invited submission for the Robert Ireland Memorial Issue.
6.  Jianfeng Li, Suwei Dong, Steven D. Townsend, Thomas Dean, Thomas J. Gardella, and Samuel J. Danishefsky*.  Chemistry as an Expanding Resource in Protein Science.  Fully Synthetic and Fully Active Human Parathyroid Hormone-Related Protein (1-141). Angew. Chem. Int. Ed. 2012, 51(49), 12263-12267.
5.  Ping Wang, Suwei Dong, John A. Brailsford, Karthik Iyer, Steven D. Townsend, Qiang Zhang, Ronald Henderickson, JaeHung Shieh, Malcolm A. S. Moore, and Samuel J. Danishefsky*.  At Last: Erythropoietin as a Single Glycoform. Angew. Chem. Int. Ed. 2012, 51(46), 11576-11584.
4.  Steven D. Townsend, Xiangyang Wu, and Samuel J. Danishefsky*.  Enhancing the Scope of the Diels-Alder Reaction through Isonitrile Chemistry: Emergence of a New Class of Acyl Activated Dienophiles. J. Am. Chem. Soc. 2012, 134(25), 10659-10663.
3.  Steven D. Townsend, Zhongping Tan, Suwei Dong, Shiying Shang, John A. Brailsford, and Samuel J. Danishefsky*.  Advances in Proline Ligation.  J. Am. Chem. Soc. 2012, 134(8), 3912-3916.
2.  Haibo Yu, Meng Wu, Steven D. Townsend, Beiyan Zou, Shunyou Long, J. Scott Daniels, Owen B. McManus, Min Li, Craig W. Lindsley, and Corey R. Hopkins*.  Discovery, Synthesis, and Structure–Activity Relationship of a Series of N-Aryl-bicyclo[2.2.1]heptane-2-carboxamides:   Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem. Neurosci. 2011, 2(10), 572–577.
1.  Alexis S. Hammond, Alice L. Rodriguez, Steven D. Townsend, Colleen M. Niswender, Karen J. Gregory, Craig W. Lindsley, and P. Jeffrey Conn*. Discovery of a Novel Chemical Class of mGlu5 Allosteric Ligands with Distinct Modes of Pharmacology. ACS Chem. Neurosci. 2010, 1(10), 702–716.

NIH Molecular Libraries Program Probe Reports
1. Yu, H.; Wu, M.; Hopkins, C. R.; Engers, J.; Townsend, S.; Lindsley, C.; McManus, O.B.; Li, M. A small molecule activator of KCNQ2 and KCNQ4 channels, 2011, Bookshelf ID: NBK121449.PMID: 23658954